A wee bit vague in your request plugyourearsde, but I can tell you that every story is essentially a WordPress post. Every post has a photo assigned to it. The PhotoPress plugin helped alot here, allowing easy upload of local images and automatic generation of thumbnails. The specific filename of the thumbnail image has to be assigned with a custom field.
The other two plugins at work here are Adhesive, which lets the administrators keep important stories at the top of the list and a massively-hacked excerpt-reloaded, which supplies the blurb for each story.
All of which is at giantmag.com…