Thanks for all the responses, good to know I am not alone with this. I have done my fair share of testing too and haven’t come up with anything as of yet.
@ nasca when I check the page source the CDN is still serving content, but I haven’t tried testing any changes to CSS or adding new images (both served from the CDN) as this is now on a live site (I did test the update on my test site, but didn’t spot this in time…).
Regrettably I have had to disable my CDN for now within the plugin and relying only on Cloudflare to keep things up to speed. I will give it a day or two and if there is no fix I will revert to the previous version of W3TC as I am out of ideas on how we might fix this short of an update.
This issue has been resolved thanks to the team at Cloudflare who couldn’t have been more helpful.
They talked me through potential solutions and within a couple of hours we had it up and running – very impressive indeed.