I mentioned in my original post that this is a clean install with no other plugins running. I have the ones that come with WP (Akismet, Hello Dolly and Jetpack) installed along with Google Analytics for WordPress but not running and deactivated WP Super Cache.
The issue was fixed by deactivating and deleting the Google Analytics plugin although I’m sure exactly what caused the conflict.
Also worth noting – I can change the title, keyword and meta descriptions individually when I’m viewing a list of all pages. It’s just not working with the ‘Edit Page’ screen (as well as not allowing updates/changes to NOFOLLOW, NOINDEX, etc).