hybridindie

Here is my WordPress multi-site with sub-domains conf. I have adapted everything above and only changed the global/wordpress-ms-subdir.conf and obviously renamed it at will. I’ve added a couple of things to make it work with 3.1 as images started failing for me when I updated to it as well as a few suggestions from various sources. Truly feedback is always welcome.

# WordPress multisite sub-domain rules.
# Designed to be included in any server {} block.

error_page 404 = @wordpress;
log_not_found off;

# This order might seem weird - this is attempted to match last if rules below fail.
# http://wiki.nginx.org/HttpCoreModule
location / {
	try_files $uri $uri/ /index.php?$args;
}

# Add trailing slash to */wp-admin requests.
rewrite /wp-admin$ $scheme://$host$uri/ permanent;

# Directives to send expires headers and turn off 404 error logging.
location ~* \.(js|css|png|jpg|jpeg|gif|ico)$ {
	expires 24h;
	log_not_found off;
}

# Pass uploaded files to wp-includes/ms-files.php.
rewrite /files/$ /index.php last;

# For multisite:  Use a caching plugin/script that creates symlinks to the correct subdirectory structure to get some performance gains.
set $cachetest "$document_root/wp-content/cache/ms-filemap/${host}${uri}";
if ($uri ~ /$) {
	set $cachetest "";
}
if (-f $cachetest) {
	# Rewrites the URI and stops rewrite processing so it doesn't start over and attempt to pass it to the next rule.
	rewrite ^ /wp-content/cache/ms-filemap/${host}${uri} break;
}

location ^~ /files/ {
	rewrite ^.*/files/(.+)$ /wp-includes/ms-files.php?file=$1 last;
}

# Uncomment one of the lines below for the appropriate caching plugin (if used).
#include global/wordpress-ms-subdir-wp-super-cache.conf;
# include global/wordpress-ms-subdir-w3-total-cache.conf;

# Rewrite multisite '.../wp-.*' and '.../*.php'.
if (!-e $request_filename) {
	rewrite ^/[_0-9a-zA-Z-]+(/wp-.*) $1 last;
	rewrite ^/[_0-9a-zA-Z-]+(/.*\.php)$ $1 last;
}

location @wordpress {
    fastcgi_pass php;
    fastcgi_param SCRIPT_FILENAME $document_root/index.php;
    include fastcgi_params;
    fastcgi_param SCRIPT_NAME /index.php;
}

# Pass all .php files onto a php-fpm/php-fcgi server.
location ~ \.php$ {
	# Zero-day exploit defense.
	# http://forum.nginx.org/read.php?2,88845,page=3
	# Won't work properly (404 error) if the file is not stored on this server, which is entirely possible with php-fpm/php-fcgi.
	# Comment the 'try_files' line out if you set up php-fpm/php-fcgi on another machine.  And then cross your fingers that you won't get hacked.
	try_files $uri @wordpress;

	#fastcgi_split_path_info ^(.+\.php)(/.+)$;
	fastcgi_index index.php;
	fastcgi_pass php;
	fastcgi_param SCRIPT_FILENAME $document_root$fastcgi_script_name;
#	fastcgi_intercept_errors on;
	include fastcgi_params;
}

location ^~ /blogs.dir/ {
      internal;
      root /var/www/nginx-default/wp3/wp-content;
}