Did install a nightly build, exact same error.
I installed the php-mysql package and /did/ restart my server and php-info shows the extension.
I worked on it for several hours, including some while talking to Mat trying to work it out. I hate to say it, but I’ve given up.
That above post was me. I just decided to register. If you have any other questions you need answered in order to give me a hand, just let me know.