Same here. Suddenly, as of today, whenever someone tries to leave a comment, it 404s on the wp-comments-post.php page.
site is http://www.mommypotamus.com
my readers are having the same problem on one of my blogs. keeps 404ing the wp-comments-post.php page, even though it’s right there in the directory.
I’m having the same issue. On every blog I’ve updated to 2.9, I get an error page when I try to first publish or save a new post. I then have to click to return back to edit posts and publish it again. Typically, the last few things I added to my post will be missing and I’ll have to re-add them (like tags, categories, images, etc).