No there are no additional setup…
My development version of WP is 3 months old, but I don’t think it makes any difference.
Are you sure it does not work ? I mean your pagination mustn’t be visible on the homepage, you need to scroll down and that’s when the pagination should be visible that it loads the new posts. Add some more posts on the homepage or reduce the width of your browser window.
Correct settings with Pronto 1.0 & Infinite Scroll 2.6.2
Content selector: #wrap
Nav selector: div.pagination
Next selector: .inactive
Item Selector: .loop-entry
enjoy !