You may want to check out WPMU:
http://mu.wordpress.org
Hi,
Just to bump an old thread I found – I’m having the same issue.
I will get around to trying MU very soon.
However, is it actually possible to run distinct sites from the same WP install? For example, I host three sites and counting, based on wordpress, on the same server. They exist in different domains and are served using virtual hosting.
It’s a bit of a pain to upgrade them all – especially since I limit the areas of the filesystem to which WP can write, ruling out auto-upgrade. I don’t particularly want to give write permissions to the WP install files to the apache process (other than uploads folder).
I was thinking that maybe I could have one install, with different wp-config files to point WP at the database for that particular site. I’d then just use a plugin “pool” in the single installation, with each site only activating the plugins it actually uses.
Thanks,
Iain