Posts in two columns

If you really want 4 columns… that picture is wrong. It should be:
post1 post3 post5 post7
post2 post4 post6 post8 etc.

With a lot of custom code and long hours of work.

Try to search for similar topics… or google.
You may find this:
http://www.cre8d-design.com/blog/2006/03/09/wordpress-tutorial-blog-posts-in-different-columns/
although the columns there are based on category.

If you really meant to have your latest 8 posts on the main page and automatically “break” them in 4 columns – that will take some time to figure it 🙁