[Plugin: WP Columns] automatic width alignment ?

can you connect it with different layouts ?

theme default I have full window wight and left and right side column

I want to divide the center column in sub-columns with your plugin

A | B | C – in ceter column by resolution 1920x…

A | B – 1400x…
C

A – 1024x…
B
C

can it be done ?

http://wordpress.org/extend/plugins/wp-columns/