Interaction with wp_nav_menu()?

So at the simplest form I have this piece of code within a pair of DIVs:

<div>
<?php wp_nav_menu(); ?>
<h1><?php wp_title(); ?> </h1>
<?php while(have_posts()) : the_post(); ?>
<p><?php the_content(); ?></p>
<?php endwhile ?>
</div>

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Every time when I click the menu link the title and content get changed accordingly, how could I make the wp_nav_menu() also dynamically interact with other DIV contents, sidebar or widgets? Please help, thanks.