dynamically change content

Hi, what I am tring to do is to set up a page that acts very much like an interface for changing a specific content area. An example might be clicking on a particular blog to view. All other items on the page would stay the same but the blog would appear in a central viewing area without everything else having to be refreshed. Is this type of thing possible? I seem to remember doing something like this with frames years ago. I wondered if there is a more modern and flexible way to do this by now. I am using a responsive theme if this helps