I am also interested in this. Can someone who has been able to get Super Cache working on IIS please post the instructions? I came across the following old article by searching on the web. But, it is 7 years old now and the instructions there are likely to be outdated.
http://blogs.iis.net/ruslany/speed-up-wordpress-on-iis-7-0
Thanks!
For the benefit of others who may run into this…
The solution suggested at the following link fixed it for me.
https://wordpress.org/support/topic/home-page-getting-a-404-error
Thanks for the idea “catacaustic”! I just now looked at that. A whole bunch of files index.html, index.htm, index.php etc. were listed against “Default document”. So, index.php was there, albeit below index.html. As an attempt, I just moved “index.php” to be above “index.html” in the priority order. But, unfortunately, that didn’t help. Simply accessing “domainName.com” still results in the same “Nothing found for requested page” error.