When I get the unexpected result error (not 404); I find the following error in the debug/log in the browser: Blocked a frame with origin “http://mysite.com” from accessing a frame with origin “https://publisherplugin.google.com”. The frame requesting access has a protocol of “http”, the frame being accessed has a protocol of “about”. Protocols must match.
I have the same issue – not been able to find a resolution yet. Tried with multiple sites, installs etc… On some installs, when saving changes I get the error “Sorry we were unable to save your configuration. The request to your server returned an unexpected result. This may be due to an incompatible theme or plugin.”