HTML CSS editor compatible with WordPress

I’ve been editing my theme templates and CSS manually, in Notepad++, using Firebug to inspect and tweak elements and Filezilla to upload the CSS files to my web server. But it seems like a very inefficient way to do it, since I have to do all that just to make one tweak, then refresh my browser to see how the page looks like with the tweaks, rinse and repeat.

I have Dreamweaver and tried to set it up with WordPress as the CreativePro tutorial suggested. It works fine with the basic site in the tutorial but not with a full WordPress site with custom theme, multiple posts, etc. I did some looking around and the problem seems to be with custom permalinks, as Dreamweaver can’t seem to handle them.

Then I looked for WordPress plugins that might allow me to edit the CSS and preview the results in real time. The only plugins I found were either very outdated or ranked very low with lots of problems.

So, how do you do serious editing to your WordPress themes? What editor do you use?