Yes – but it also kind of depends on what your expectation of “work with” means. BuddyPress extended profiles do not use the WP user meta table, and there are certain “pages” that BP creates that work outside what WP-Members handles.
The plugin itself is freely available, so you can try it out and see if it meets your needs.
There is also an Advanced Options extension available for premium support subscribers, and that extension has, among other things, additional settings specific to integrating with BuddyPress. It has settings to handle the groups, activity, and members pages by redirecting them to the login page, and also shuts off feeds. You can see an overview of the extension’s features here:
https://rocketgeek.com/plugins/wp-members/extensions/advanced-options/
