Multisite – Different directory structure

I have an html static site with multiple languages (i’m using subdirectory strategy), which looks like this:

domain.com/br/

And I have a WP installation at

domain.com/br/blog/

I’m planning to turn my WP to multilanguage and I need to know if it’s possible to use one single WP Core Installation and deal each language as a different site.

I need that

domain.com/br/blog

and

domain.com/us/blog

be the same WP installation (each one with it own content, but same structure). Is that possible? Should I install one WP Core in /us/blog/ and /br/blog/? If so, how can I deal with multilanguage options?

Thank you in advance!