Errors after updating wordpress

After updating to WordPress 3.1.2 manually, I got this warning and error. I can no longer see my website nor log-in to wordpress.
How do I solve this issue?
Please help!

Warning: require(C:\Inetpub\vhosts\forward.com.ph\httpdocs/wp-includes/load.php) [function.require]: failed to open stream: Permission denied in C:\Inetpub\vhosts\forward.com.ph\httpdocs\wp-settings.php on line 19

Fatal error: require() [function.require]: Failed opening required ‘C:\Inetpub\vhosts\forward.com.ph\httpdocs/wp-includes/load.php’ (include_path=’.;./includes;./pear’) in C:\Inetpub\vhosts\forward.com.ph\httpdocs\wp-settings.php on line 19

Please tell me how to troubleshoot this one.