Sick and tired of maintaining several blog installations? Want one WordPress installation to rule them all? Try this plugin.
This plugin assists with the creation of multi-blogs on top of Virtual Multiblog, so that all blogs are powered by a single WordPress code base. It also assists with proper Virtual Multiblog setup.
Check out the plug-in homepage for in-depth information about the plug-in.
Attention: This version has only been tested with a standard WordPress installation, and it works well under such conditions. However, it could have issues when a wp-config.php has been manually tweaked significantly, though this is quite unlikely.
It also relies heavily on a specific work flow with Virtual Multiblog, so it may not work propertly with manual VMB setups that differ from the assumed work flow.
Having said that, it is fairly safe to use the plugin. It creates a backup of wp-config.php before touching it, and supports a "dry mode" where you can see what would be written to what filte before actually writing anything.
And remember: Backup early! Backup often!