I've tried both WP super cache and W3 Total Cache with this plugin, and when either of those caching plugins are enabled, the lightbox images don't load anymore. The lightbox itself loads, but no image.
With W3, deactivating the plugin allows it to work. With WP super I had to actually delete the plugin, not just deactivate it.
Weird...any thoughts on this? I've seen this happen so far on WP 3.7.1 and WP 3.6.1. Thanks!