If you download the development version from the download page you should notice a nice speed boost if you have compression turned on.
There was a minor bug where the data to be sent to anonymous users was compressed twice. That's fixed in the dev version but I'd like to have people test it before it goes live.
Make sure you take note of the before and after page generation times. Hopefully they'll be cut almost in half (except if you have really lousy plugins that take ages anyway, YMMV)