Yes. Effectively, if you can "say" the text, Dragon can find it and move the focus to it. You get extra bells & whistles if you use it in conjunction with IE but it's still eminently usable in Firefox (which I what I used it with for 6 months).
Using the new Add Media might be a bit more cumbersome as the files don't have displayed names/titles, so - at worst - you'll have tab through the thumbnails to get to the image that you want or use the Search option if you know the title of the image. Hopefully, that's something that we can change in future versions of WordPress via input from
Make WordPress Accessible. Other than that, I'm not aware of any major problems for VR users right now. Certainly I think we've managed to address some issues in Appearance -> Menus in WordPress 3.6 and there are plans to improve Appearance -> Widgets further (you can use the accessibility option for now).
Do feel free to join Make WordPress Accessible if you'd like to lend a hand and give us your feedback/thoughts.