I've been testing 3.5RC with no significant issues. I did however notice Hyper is throwing some errors.
First error is:
Notice: Indirect modification of overloaded property hyperdb::$dbh2host has no effect in /var/www/__/docs/wp-content/db.php on line 604
Notice: Undefined property: hyperdb::$dbh2host in /var/www/hostrevo/docs/wp-includes/wp-db.php on line 575 Notice: Undefined property: hyperdb::$dbh2host in /var/www/__/docs/wp-includes/wp-db.php on line 575