I've been experiencing a lot of problems with WP-Spam Free installed.
First, I sometimes get a "blank screen" in the Admin panel.
Second, it seems to conflict with the WP Comment Remix plugin. I cannot reply to comments with WP Comment Remix unless I turn off WP Spam Free.
I just upgraded to 2.6.1 using Instant Upgrade plugin. After the upgrade, I could not get into the WP Admin area - I got an Internal Server 500 Error. When I manually removed WP-Spam Free from my plugins folder, I was able to log in without any problem.
I could not get WP Automatic Upgrade to work with WP-Spam Free. When I deactivated WP-Spam Free, it worked fine.
I really appreciate your help. If I can't get it to work, what's another good spam plugin?