I've been using WP e-Commerce for about 5 years and each new product release has always had some bugs in the initial release but they eventually fix the items.
Don't get me wrong, I've used simple paypal shopping cart and it works great for a really, really simple cart...but if you want multiple options and variations Wp e-Commerce is the closest to perfect that you're going to get. The key is to know someone who knows how to find the bug and fix them.
I've fixed almost 50 bugs in that past 5 years and my clients are always happy as clams!!
I'm going to give you a full proof way to make sure your WP e-Commerce admin dashboard "always" works.
Step 1: Totally remove the WP e-Commerce from your website, both by FTP and remove it from your MySql Database as pieces of code usually linger on within the database. Don't load it back in just yet.
Step 2: Enable either Twenty Ten or the new Twenty Eleven as they are very, very simple configured templates for WordPress.
Step 3: Re-upload a clean and fresh copy of your WP e-Commerce plugin but do not enable it just yet.
Step 4: Turn off all of your active plugin's and then enable the WP e-Commerce plugin. (if you are using a Gold Cart extension to this plugin...do not enable it yet).
Step 5: Now access your admin dashboard for the plugin and you should have a fully operating WP e-Commerce now. Best thing to do is configure your settings, then turn on Gold Cart and then turn one each of your other plugins one at a time as you may have another plugin that is not compatible to the ecommerce plugin.
Final Step: If you're eCommerce plugin is now working correctly....enable your Primary Theme at this time....what these steps will do is eliminate each item that may affect this plugin.
Thanks again, RC