I'm using the latest 2.0 beta4 version of the Podcasting plugin and everything works fine. Except when playing files in the audio-player in my browser (tested in safari 3 and firefox 3) after some minutes (ususally around 13min), the playback restarts from the beginning. all my files are encoded as mp3s with 64kbps and 44.1kHz mono. I don't know if this is a problem with the audio-player or the plugin settings. The problem already existed in WordPress 2.6.
you can find the page here.
Otherwise thanks for this great plugin!