I'm using a vanilla install of the Thematic theme on my website. A few minutes ago I installed the latest version of the AJAXd WordPress plugin on the same site, which resulted in pages not properly loading. When I clicked in a link to ether a page or blog entry, it looked as though the entire site was being loaded in the content area, but only the header of the requested page.
Also, activating the plugin resulted in my permalinks doing strange things.
I wish I had more info about the issue to give, but I do not. If I can be of assistance in isolating the problem, let me know.