I am currently running into a permalink issue, whenever we update a page the permalinks breaks down and we get an error 404 on every page. We have to change the permalink structure back to the basic and change it back to the custom type.
This issue seems to have been happening since WP 2, and I've been seeing a lot of closed threads. I've already tried a couple of the suggestions such as making the directory write protected for the .htaccess, but it doesn't seem to be an htaccess issue because there doesn't seem to be any changes to the htaccess whenever we edit the posts.
Sorry if there is already an existing thread for this, maybe I can be redirected to the proper thread if ever.