I just signed up for PerformancingAds and was a little bummed to see their system installed a plugin with a PHP call to grab the ads. After Otto explained to me that the whole point of WP-SuperCache is to make the site static and *not* run any PHP, I realize that WP-SuperCache is likely to prevent the plugin from displaying new ads, more or less defeating the purpose. If any of my space actually sells, I'd have to manually dump the cache to force them to be displayed.
I'd really like to give this new advertising network a shot, because it looks like other blogs have been successful selling cheap space. That said, a PHP-only solution is not friendly to what I've got to imagine is an ocean of installs running some sort of caching to keep access times reasonable.
Here's the plugin URL: