I just upgraded to 2.6.1 and now my front page displays this error:
Sorry, but you are looking for something that isn't here.
I read other posts about this error that suggested that the blog does not contain any posts, but that is not the case here. I have 114 posts on my blog. If I click a category or archive it works fine, just doesn't display anything when visiting the front page or root of my domain.
You can view my site here: http://www.thebdbulls.com