I'm running 3.3.1 and I keep running into this "No Input File Specified" issue. It doesn't last forever, eventually the site loads again as normal - takes about 5-10 minutes.
It affects both the Admin and Front-end of the website. It seems to occur only after I update a post, page or add an image.
I've searched through the forums and can't seem to find a solution for me. I upgraded to 3.3.2 and thought that was the issue, and I downgraded. But I still get the same issue.
I run a number of WordPress Sites and I've never encountered this problem before on any other site I own.
Someone please help a fellow WP'er out!