I have had this problem before, with NextGen and Wp E-commerce running.
When you click an image in the gallery, a bunch of thumbnails appear in the picture. But the in the shopping cart, it works fine.
In th eold version, I went into WP E-commerce and deleted the contents out of the thickbox.js file. And it worked. But both plugins are updated, and that fix doesn't work.
If someone could give me a fix to this, it has to be thickbox.js issue, that would be great. Thank you