I like it to install wordpress in a subfolder and place just the index.php to the root directory. I know that this was not possible with the 'old' wordpress multiuser. However, I tried it with wordpress 3.0 multiuser and it looks as if there are no problems at all.
Are there known issues with multiuser if wordpress url and siteurl are different? I tried creating new blogs, uploading images and I didn't experience any problems so it *SEEMS* to work fine. However, I would rather prefer to be sure :-)
Thanks for any infos on this.