Since WP 3.5 there is an error when saving posts when Focal is enabled (line 980 in focal_wp28.php). To fix this, replace the line
$querystr = $wpdb->prepare($querystr);
$querystr = $wpdb->prepare($querystr,null);
That solved the issue for me. Thanks to http://wordpress.org/support/topic/missing-argument-2-for-wpdbprepare?replies=2, it seems that other plugins are affected, too
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