Pods is incredible. Scott has worked long hours to get Pods 2.0 out the door, and his work has really shined. Everything about this plugin is polished, even the installation screens. It's a huge step forward from Pods 1.x.
Pods lets you add custom post types and taxonomies. It lets you add custom fields to post types, users, comments, taxonomies. It has front-end forms, migration tools, 2 different storage options (meta vs. table-based). Seriously, there's not a whole lot this plugin DOESN'T do.
The only issue with Pods is that, with so much functionality, there's somewhat of a learning curve. Scott is usually on IRC or the forums to help answer questions.