Fatal error on line 17 in index.php – no such file or directory ??

I know the directory and files all exist and are in the right place. But when I load the index page of my wordpress site, I get this:

Warning: require(./wp-blog-header.php) [function.require]: failed to open stream: No such file or directory in G:\inetpub\vhosts\alyshameeks.com\httpdocs\myword\index.php on line 17

Fatal error: require() [function.require]: Failed opening required ‘./wp-blog-header.php’ (include_path=’.;./includes;./pear’) in G:\inetpub\vhosts\alyshameeks.com\httpdocs\myword\index.php on line 1

I don’t know where it’s getting “G:\inetpub\vhosts\” before my domain from, but I’m sure it’s probably correct…

Anyone??