I have an issue with a local install of WP3.8 under WAMP on Win7. I had originally experienced the same issue with WP3.7 and updated to see it it fixed the issue but it didn't.
When I try to edit/crop an uploaded image with Google Chrome (ver. 32.0.1700.41 m Aura).
When the 'Edit Media' page loads the image appears for a few moments then is replaced with a broken image icon.
In the browser console it flags the following error.
This feature works correctly on IE11, FF and Safari.
I have already disabled and/or deleted all the plugins and switched back to the default WP themes, but it's made no difference.