To be honest there is very little interaction between them anyways. Initially I wanted to use WordPress as a CMS and a blogging platform. But if that is only possible by changing the structure of my site I'd rather keep the two functions separate. And plus it is almost as quick for me to edit and upload content in my static pages from coda as it is to go into wordpress and edit them in the html view which is what I would use.
Does this make sense?
Well, if you want to use WordPress as a CMS - that is, as the system to manage your content, then yes, you'll have to restructure a bit. WordPress can only know about content that is in its database.
Really, it's all a matter of what works best for you.
I took that route (WordPress only for my blog posts, and static HTML for everything else) for several years, before porting all of my static HTML content into WordPress. It took a while to port, but once done, I am so glad that I did, and I would never go back.