I just updated to WordPress 2.8.2. on three blogs I maintain. [Word to the wise: better to update one blog and see how things go. Now I have three blogs with trouble.]
For example, at AmericanFreethought.com when I create a new entry I can type the names of new tags into the slot, but nothing happens when I press the Add button. Similarly for new Categories or to add an image.
Frankly, I'm surprised something so basic as this slipped through the Beta process.