Well, couple problems.
In IE on a 1240x768 screen resolution:
The "Numbers" box on the right side has some sort of error in it. The box is extended out to the right. It says "185 posts
87,962 post words
8,924 comment words
9 registered users
Warning: strtotime() [function.strtotime]: Called with an empty time parameter. in /home/tyler/domains/tylerwillis.com/public_html/wp-content/plugins/wp_jvisitors.php on line 204
The middle section section just below the top post has been pushed down the page to where the right sidebar ends.
Personally, although I do love using colors myself, I feel there's a bit too much in the way of color/graphics going on in the sidebars. Perhaps if you reduced the number of different colors, or simplify the graphics - you've got a different color and texture inside every box in the sidebars, and personally, your content is the last thing I'm looking at because I'm trying to make sense of what's going on in your sidebars. It's a bit distracting. Just my opinion.
It looks much better in Firefox, no errors, and all your content seems to be in the appropriate places.Hope that helps. :)