Just upgraded to 2.6.1 . So far so good, however some bugs seem to occur for me.
Whenever i write a post and hit the post button, my page goes to an error 404 with the url stating http://xxxx.xxx/wp/wp-admin/post.php as being non-existant. Now when i refresh the page to http://xxxx.xxx , the post which i wrote will be there. This happens for both post and page and link.
Now the same problem occurs if it was Manage->post/page/link . As soon as hit save, i go to a 404. But when i go to the main permalink the edits are there.
Last issue i have is that i have a major white space between my main contents and footer but not in the permalink or page.