Website jumbles

I have gone through technical support at BlueHost and Tips and Tricks for their estore plug in. I only have estore, affiliate and Instabuilder plugins, and my website keeps jumbling up. It will be fine, I open it back up and everything is all over the place. It is costing me sales.

Also, I have comments shut off for posts and am receiving hundreds of spam a day.

I started a clean site a few months ago, and tech at Bluehost said it is a WP issue.