nwtarr, I can relate. Gets to the point you just want to curse.
From a fresh install, 2.2.2 spat out a host of error messages. I had to post for help. This is a fresh instal, you understand? Now I can't upload images into my posts like I could before. I get this error:
The uploaded file could not be moved to /home/cecon46/public_html/whatsmellssogood/wp-content.
Warning: Cannot modify header information - headers already sent by (output started at /home/cecon46/public_html/whatsmellssogood/wp-admin/admin-functions.php:1986) in /home/cecon46/public_html/whatsmellssogood/wp-includes/functions.php on line 1357
But wait, the story doesn't end here. All of a sudden and without me having done anything, one of the new blogs started to work (uploading images). But the other one still gets this message. I am beyond stumped.