I updated from 2.1.3 to 2.2 via script of fantastico before 10 days. I had problem with my fonts so I restored from my back up but now I had several problems. Scheduled post are not posted. I made my question to to forum but nobody answered how it will be working again.
After the first problem that I saw there much more. My posts now do not ping to other wordpress blogs so readers can see that I wrote about the post. (techoratti stil finds that).
Today I tried to search comments for nicknames but it wasn't searching at authors of comments but only within the comment.
About font problem I don't know can be solved and go to 2.2 version again ( I am at midphase server).