I'm moving to a dedicated host from a VPS because of load issues, and considering a switch to nginx in the process. I'm not an experienced server admin - when I need to do anything with a server, I just find instructions online and follow them. Nginx is appealing for the performance upgrade, though I'm concerned that I might be in the dark when facing any issues with it.
To those in WP.org-land who know something about WP + nginx - how easy is this to setup and maintain? What are the issues you run into when using WP + nginx? I'm using BuddyPress, with multisite/subdomains - anyone out there happily using a similar setup on nginx? Do you consider the performance upgrade truly dramatic enough to warrant moving from Apache?