Hey, i've had this exact same problem - It started without me doing anything to the site, with the old version of wordpress (2.3.x i think) so i thought i'd upgrade to try and fix the problem, but it's not helped..
The weird thing is though, when i try and make an edit it redirects me to the actual domain root, as in "www.everythingitunes.com" when the wordpress install is in a subfolder of the domain - "www.everythingitunes.com/os/windows".
I have two wordpress installs, one in /os/windows and one in /os/mac, and they both redirect back to the main page. I've tried deleting and recreating all my .htaccess files but nothing changed...
People have also reported problems with getting blank pages when trying to comment. I've tried anything i can think of, such as using the default theme, and disabling all plugins etc.
Sometimes, if i leave the edit page open, after exactly one minute, it seems, the homepage loads in one of the frames of the edit page..
See screenshots... (in particular, look at after - part 4.
[BEFORE] http://i27.tinypic.com/2hn6dsp.jpg
[AFTER - Part 1] http://i25.tinypic.com/15d57nm.jpg
[AFTER - Part 2] http://i28.tinypic.com/1534ahl.jpg
[AFTER - Part 3] http://i29.tinypic.com/2cdhiir.jpg
[AFTER - Part 4] http://i30.tinypic.com/2yn00eh.jpg
Thanks in advance for any help..!