podPress 8.8.4 does not work with WP 3.0. But there is a Development Version which has been tested with WP 3.0 in SingleSite and MultiSide Mode successfully. But is still a Beta version because it is possible that it includes still some bugs.
I would appreciate it if you could help me testing and finding these bugs.
Test this Development Version in save environment (not in your productive blog). Because this is a Beta: please make backups of all of your blog files, folders and the data base before you start testing!
Please, report your experiences (good and bad) with this Beta version here.