Twitter.com is down as of this forum post. It seems Twitter-tools wants to contact twitter.com on almost any page in the wp-admin interface. This means to do anything when twitter.com is down takes a minute or 2 while I wait for the connection to twitter.com to timeout.
Can you fix Twitter-Tools so it only contacts twitter.com when you post, not on every admin page when loading?
Besides that, I love the plug-in. Thanks for the great work!