When you upload another pic after a first one, the preview still show the previous one, because the browser cached the previous thumbnail image.
Adding a random value (i.e &random=128578291752891) at the end of
/wp-content/plugins/simple-post-thumbnails/timthumb.php?src=/wordpress/wp-content/thumbnails/1.jpg&w=200&h=150&zc=1&ft=jpg will solve this issue.