After a disater yesterday and reading you encouraging words, I took the plunge. I did try the plugin and thank you - yes it worked brilliantly!
My site is portfolio based and has 30 images (crunched) on main page and your plugin cut loading time from: 17.9 to just .46 and it didnt brake a sigle slide show or affect any of the java function and timthumb images are working fine also :)
As I've been looking at this issue for over a week now which led me to try something else, went on and added another plugin. DB cache reloaded and together they have cut the loading time now down to .42 and both seem to be working fantastically together too. I would still like to try to find ways to further cut my loading time but with a large image based blog - this is going to be hard to beat I think!
Can't thank you enough, donation on the way at the end of the week :)